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Laser Beauty Equipment
Skin starts showing its first signs of aging in the late 20s to early 30s and it usually presents with wrinkles, dyspigmentation, telangiectasia, and loss of elasticity. Common histologic and molecular-level features are reduction in the amount of collagen, fragmentation of collagen fibers, elastotic degeneration of elastic fibers, upregulation of matrix metalloproteinases (MMPs), especially MMP-1 and MMP-2, dilated and tortuous dermal vessels, and atrophy and disorientation of the epidermis.23,24 Both chronological and environmental influences are responsible for the aging process of skin; however photodamage seems to be one of the most important causes of these changes.
Figure 3
Examples of LLLT devices in dermatology for home and clinical use.
Figure 4
Figure 4
Possible mechanism of actions for LLLT’s effects on skin rejuvenation.
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LLLT for Acne
Pathogenesis of acne vulgaris has not yet been clarified, however current consensus is that it involves four main events: follicular hyperconification, increased sebum secretion effected by the androgenic hormone secretions, colonization of Propionibacterium acnes and inflammation.49 P. acnes plays a key role by acting on triglycerides and releasing its cytokines which in turn trigger inflammatory reactions and alter infundibular keratinization.49 Current treatments for acne vulgaris include topical and oral medications such as topical antibiotics, topical retinoids, benzoyl peroxide, alpha hydroxy acids, salicylic acid, or azaleic acid. In severe cases, systemic antibiotics such as tetracycline and doxycycline, oral retinoids, and some hormones are indicated.50 Medications work by counteracting microcomedone formation, sebum production, P. acnes, and inflammation.50 Despite many options that are available for treatment of acne vulgaris, many patients still respond inadequately to treatment or experience some adverse effects.
Phototherapy (light, lasers, and photodynamic therapy) has been proposed as an alternative therapeutic modality to treat acne vulgaris and was proposed to have less side effects compared to other treatment options.51 Exposure of sunlight was reported to be highly effective for treatment of acne with efficacy up to 70%.52 The sunlight decreases the androgenic hormones in the sebaceous gland, but the unwanted effect of exposure to UVA and UVB limits sunlight for the treatment of acne. Recently, phototherapy with visible light (mainly blue light, red light or combination of both) started being used in the treatment of acne (Figure 3).52 One mechanism of action of phototherapy for acne is through the absorption of light (specifically blue light) by porphyrins that have been produced by P. acnes as a part of its normal metabolism, and that act as endogenous photosensitizers. 49,53 This process causes a photochemical reaction and forms reactive free radicals and Singlet oxygen species which in turn lead to bacterial destruction (Figure 5).49,53 Red light is known to penetrate deeper in tissues when compared to blue light.50 It has been demonstrated that red light can affect the sebum secretion of sebaceous glands and change keratinocyte behavior.54 Furthermore, red light might also exert its effects by modulating cytokines from macrophages and other cells, which in turn could reduce inflammation.51,54
Figure 5
Figure 5
Illustration of acne treatment with red and blue light.
What is laser therapy used for?
Laser therapy may be used to:
shrink or destroy tumors, polyps, or precancerous growths
relieve symptoms of cancer
remove kidney stones
remove part of the prostate
repair a detached retina
improve vision
treat hair loss resulting from alopecia or aging
treat pain, including back nerve pain
Lasers can have a cauterizing, or sealing, effect and may be used to seal:
nerve endings to reduce pain after surgery
blood vessels to help prevent blood loss
lymph vessels to reduce swelling and limit the spread of tumor cells
Lasers may be useful in treating the very early stages of some cancers, including:
410nm B-light sterilize Mechanism:
1. The locally generated singlet oxygen sterilization
2. Enhanced phagocytosis of white blood cells, improve the body immunity
650nm R-light activate cells Mechanism:
Mitochondria and human tissue absorption spectrum of resonance in the mitochondria, catalase,superoxide dismutase activity to be excited, promote cell the new supersedes the old., can eliminate the harmful substances generated in the process of organism in the new supersedes the old.,enhance skin elasticity, promote tissue repair.
How to use
1. Cleaning before treatment
Clean the skin(wash) and Clean the Treatment lense with glass cleaning cloth(wipe)
2. Preparation
Electric connect: Connect adaptor
Timer: 1/2/3 gears, select by pressing the shift button
Gnt Model:10/20/30 mins
P Model:5/7/10 mins
Turn on: Press the button, turn on the light,Do not look steadily at the light
3. Treatment
Let light illuminate the skin with a distance about 1-2 cm. Hold until the timer runs out with buzzing.
4. Treatment Plan
Eczema and Neonatal red buttock:we suggested treatment timer is 10-20 mins
Acne,Pimples, Stain and Dull: we suggested treatment timer is 20-30 mins
Pustule:we suggest treatment timer is 30 mins
Cnt Model: 1-2 times per day,the suggested treatment period is 7 days.
P Model: 2-3 times per day, the suggested treatment period is 7 days.
This is a basic method of exfoliation using a hand-held device that propels a high-speed flow of aluminum oxide crystals onto the skin. At the same time, the machine’s vacuum system sucks away dirt and dead cells from the epidermis (the outer layer of skin). The condition of your epidermis determines how fresh your skin looks, and how well your skin absorbs and holds moisture. Higher-end clinics use diamond-tipped microdermabrasion machines that don’t require a bowl of water with a face towel on top of it, because the machine is “cleaner.” Instead of blasting crystal particles on the patient’s face and then scrapping it off, the tip is encrusted with micronized diamond particles so every stroke across the face feels less scratchier on the skin and doesn’t leave behind crystals. However some skincare experts feel that there’s not a significant difference between crystal and diamond microdermabrasion, but I disagree (I think these experts also shop at H&M – call me a skincare snob #idontcare). Crystal microdermabrasion feels like someone is scrapping your face with a butter knife while diamond microdermabrasion feels like gentle whisking.
Large quantity enjoy more discounts.
Wholesalers/resellers or distributors are more than welcome.
We will be happy to offer the best price with discount for multiple terms.
Guarantee & warranty
100% guarantee on all our laser therapy device, beauty and healthcare equipment! All machines comes with 1 years full warranty, but honestly we will offer you life time free online advise, help and the best after sale service even after years, so if you buy the machines from us, we will aleays be there for you!
Training
There are user manual and maintenance manual to guide you operating the machine.
cervical cancer
penile cancer
vaginal cancer
vulvar cancer
non-small cell lung cancer
basal cell skin cancer
For cancer, laser therapy is usually used alongside other treatments, such as surgery, chemotherapy, or radiation.
Laser therapy is also used cosmetically to:
remove warts, moles, birthmarks, and sun spots
remove hair
lessen the appearance of wrinkles, blemishes, or scars
remove tattoos
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LLLT for Photoprotection
It is widely accepted that the UV range (< 400 nm) exposure is responsible for almost all damaging photo-induced effects on human skin.57–59 Some proposed mechanisms for UV induced skin damage are collagen breakdown, formation of free radicals, inhibition of DNA repair, and inhibition of the immune system.57–59 Existing solutions to prevent UV induced damaging effects are based on minimizing the amount of UV irradiation that reaches the skin, which is achieved by either avoidance of sun exposure or by use of sunscreens. However sometimes sun avoidance might be hard to implement, especially for the people involved in outdoor occupations or leisure activities. On the other hand, the photoprotective efficacy of topical sunscreens have their own limitations as well, which include decreased efficacy following water exposure or perspiration, spectral limitations, possible toxic effects of nanoparticles that are contained by most sunscreens,60 user allergies, and compliance.
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LLLT for Herpes Virus Lesions
One of the most common virus infections is caused by herpes simplex virus (HSV). HSV is chronic and lasts one’s entire life. The exposure of the host to several kinds of physical or emotional stresses such as fever, exposure to UV light, and immune suppression causes virus reactivation and migration through sensory nerves to skin and mucosa, localizing particularly on the basal epithelium of the lips and the perioral area.69 Up to 60% of sufferers will experience a prodromic stage, after which the lesions develop through stages of erythema, papule, vesicle, ulcer and crust, until healing is achieved. It is accompanied by pain, burning, itching, or tingling at the site where the blisters form. Immune responses to HSV infection involve: macrophages, Langerhans cells, natural killer cells, lymphocyte-mediated delayed-type hypersensitivity, and cytotoxicity.70
While several anti-viral drugs such as acyclovir and valacyclovir are used to control recurrent herpes outbreaks, only limited reduction in the lesions’ healing time has been observed.69 Furthermore, development of drug-resistant HSV strains is of increasing significance especially in immunocompromised patients.70 Therefore, new therapy modalities that can shorten the recurrent episodes and cause prominent reduction of related pain and inflammation are necessary.
LLLT has been suggested as an alternative to current medications for accelerated healing, reducing symptoms and influencing the length of the recurrence period.69,71,72 Among 50 patients with recurrent perioral herpes simplex infection (at least once per month for more than 6 months), when LLLT (690 nm, 80 mW/cm2, 48 J/cm2) was applied daily for 2 weeks during recurrence-free periods it was shown to decrease the frequency of herpes labialis episodes.73 In another study with similar irradiation parameters (647 nm, 50 mW/cm2, 4.5 J/cm2), investigators achieved a significant prolongation of remission intervals from 30 to 73 days in patients with recurrent herpes simplex infection.74 Interestingly, patients with labial herpes infection showed better results than those with genital infection. However, irradiation did not effect established HSV latency in a murine model.75
Large Image : Black head white head removal machine acne soft laser pen for acne removal
Product Details:
Place of Origin: China
Brand Name: THB
Certification: CE/ROHS/FCC/SGS
Model Number: TM-MR-134
Payment & Shipping Terms:
Minimum Order Quantity: 50pcs
Price: negotiation
Packaging Details: Packed in carton firstly,and then reinforced with wooden case for outer packing
Delivery Time: 10 working days after received your payment
Payment Terms: T/T or western Union
Supply Ability: 3,000pcs per month
Laser Removal Scars Soft Laser Skin Anti-aging Acne Treatment Facial Beauty USA
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NEW 650nm Nasal Soft Laser therapy LLLT Nose Acupuncture allergic rhinitis
B
Even though mechanism of action is still not clear, an indirect effect of LLLT on cellular and humoral components of the immune system involved in antiviral responses rather than a direct virus-inactivating effect was proposed.76 Inoue et al. investigated tuberculin reactions at the bilateral sites of the backs of sensitized guinea pigs. They applied a single low-power laser irradiation dose at a fluence of 3.6 J per cm2on one side and compared it to contralateral non-irradiated sites.77 Interestingly, following irradiation, tuberculin reaction was suppressed not only at the irradiated site but also at the contralateral nonirradiated site. It is worth to note that this phenomenon was observed when mononuclear cells were dominant in the perivascular cellular infiltration. Based on their results, they have suggested a possible systemic inhibitory effect of LLLT on delayed hypersensitivity reactions.77 Activation and proliferation of lymphocytes78–81 and macrophages82 as well as the synthesis and expression of cytokines83,84 following low intensities of red and NIR light have been reported by several investigators. The question of whether these effects of LLLT have any influence on HSV infection remains to be determined.
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Several studies reported that LLLT in Soft Laser Beauty the red to near infrared spectral range (630–1000 nm) and nonthermal power (less than 200 mW) alone or in combination with other treatment modalities (mainly blue light), is effective for treatment of acne vulgaris.17,49,52,54,55 One of these studies demonstrated significant reduction in active acne lesions after 12 sessions of treatment using 630-nm red spectrum LLLT with a fluence of 12 J/cm2 twice a week for 12 sessions in conjunction with 2% topical clindamycin; however the same study showed no significant effects when a 890 nm laser was used.50 A few studies also showed that the combination of blue light and red light have synergistic effects in acne treatment.49,54–56 It is proposed that synergistic effects of mixed light is due to synergy between the anti-bacterial and anti-inflammatory effect of blue and red light respectively (Figure 5).49,56 It is also worth mentioning that in most studies improvement in inflammatory lesions were higher than the improvement in comedones.49,56
Soft Lazer
For turning back the clock on your skin's appearance, fighting off unwanted pimples or reducing those dark pigmentation marks, you can't find a better treatment than a relaxing cold laser facial. Soft Laser or Cold Laser is a painless treatment that offers a natural mode of treatment and does not produce any heat and does not cut through skin. This treatment has no side effects.
Bio Magnetic Micro Dermabration
Biomagnetic Microdermabration is a Unique and VERY Specialised treatment where a medical designed magnet along with a magnitiseable product is used to eliminate the superficial layer of the skin. Magnificent results are obtained for lifting and firming of sagging and puffy skin, the lightning of pigmentation marks and a brilliant antibacterial treatment for Acne.
Schiatu
This treatment is a scientific form of “touch communication,” by working on the facial pressure Soft Laser Beauty points, using our medical Magnet. Our Shiatsu treatments are extremely effective and are used for a variety of ailments, from sinusitis problems, to headaches or migraines.
Biotech
The unique fusion of actives, touch & technology to help reboot cellular performance,enhancing the skin’s ability to repair and renew. Extraordinary results after just one treatment.
Laser therapies are medical treatments that use focused light. Unlike most light sources, light from a laser (which stands for light amplification by stimulated emission of radiation) is tuned to specific wavelengths. This allows it to be focused into powerful beams. Laser light is so intense that it can be used to shape diamonds or cut steel.
In medicine, lasers allow surgeons to work at high levels of precision by focusing on a small area, damaging less of the surrounding tissue. If you have laser therapy, you may experience less pain, swelling, and scarring than with traditional surgery. However, laser therapy can be expensive and require repeated treatments.
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China Electronic circuit board, PCBA manufacturing
3
US$ 1.6 - 1.8 / Piece
1 Piece (Min. Order)
Freight Cost Available
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PCB & PCBA OEM Manufacturer Electronic Circuit Board Elec...
China PCB & PCBA OEM Manufacturer Electronic Circuit Board Electronic PCBA Manufacturer
1
US$ 1.5 - 2 / Piece
1 Piece (Min. Order)
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Electronic PCB manufacturing PCBA
China Electronic PCB manufacturing PCBA
1
US$ 0.1 / Piece
500 Pieces (Min. Order)
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Custom Electronic PCB Manufacturing Power Board 14.8V Rec...
China Custom Electronic PCB Manufacturing Power Board 14.8V Rechargeable Battery PCM
4
US$ 4.99 - 5.23 / Piece
10 Pieces (Min. Order)
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Impedance control PCB assembly, electronic PCBA manufactu... New
China Impedance control Soft Laser Beauty PCB assembly, electronic PCBA manufacturing
PCB Electronic Contract Manufacturing, Laboratory Instruments PCBA Turnkey Assembly with Box Building
US $0.3-7 / Piece
1 Piece (Min. Order)
Model Number: PCBA
Base Material: FR4, teflon, aluminum base, copper base, steel base, high frequency
Min. Hole Size: 0.1mm(4mil)
Min. Line Spacing: 4mil
Copper Thickness: 0.5oz-6oz
Board Thickness: 0.1 to 6.0mm(4 to 240mil)
PCB Electronic Contract Manufacturing, Laboratory Instruments PCBA Turnkey Assembly with Box Building 3 Photos
Shenzhen Kingsheng Pcba Tech. Co., Ltd.
China (Mainland)
Transaction Level:
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63.0%
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smart Instrumentation instrument pcb/pcba Manufacturer Circuit Board Assemblies for Instrumentation Products
US $1-10 / Piece
1 Piece (Min. Order)
Base Material: FR-4 epoxy resin,fr-4,cem-1,cem-3
Surface Finishing: HASL/ ENIG /OSP,ENIG HASL OSP
Min. Hole Size: 0.2mm(8mil) pcba
Min. Line Spacing: 0.1mm(4mil) pcb
Copper Thickness: 1/2OZ 1OZ 2OZ 3OZ
Board Thickness: 1.6mm-3.2mm,0.2mm--3.2mm
smart Instrumentation instrument pcb/pcba Manufacturer Circuit Board Assemblies for Instrumentation Products 6 PhotosVideo
BLD Electronic Co., Ltd.
China (Mainland) Trade Assurance
Transaction Level:
6 Transactions(6 months)
70,000+
Response Rate
90.7%
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Customized design turnkey manufacturer PCB PCBA for musical products/ guitar board/ instrument
US $0.5-10 / Piece
1 Piece (Min. Order)
Place of Origin: Guangdong,China (Mainland)
Surface Finishing: HASL,HAL-LF,OSP ENIG etc
Min. Hole Size: 0.2mm
Min. Line Width: 0.1mm
Min. Line Spacing: 0.1mm
Copper Thickness: 1-6OZ
Customized design turnkey manufacturer PCB PCBA for musical products/ guitar board/ instrument
Shenzhen Rayming Electronic Co., Ltd.
China (Mainland)
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55.6%
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High quality pcba Manufacturer 94v0 pcb Circuit Board assembly PCBA for Intelligent instrument
US $2-10 / Piece
1 Piece (Min. Order)
Place of Origin: Liaoning,China (Mainland)
Brand Name: JY
Model Number: JY PCBA
Base Material: FR-4, fr-4,cem-1,cem-3
Surface Finishing: HASL,ENIG
Board Thickness: 0.2mm--4mm,0.2mm-4.5mm
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Dalian JY Electronic Technology Co., Ltd.
China (Mainland) Trade Assurance
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42 Transactions(6 months)
500,000+
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100.0%
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Sensors PCB For Medical Instrument Manufacturer
US $0.001-0.03 / Piece
1 Piece (Min. Order)
Min. Hole Size: 0.2mm
Copper Soft Thickness: 0.02mm (through hole copper),1/2OZ 1OZ 2OZ 3OZ
Surface Finishing: OSP HAL Immersion Tin/ Gold,HASL\OSP\DOLD Finger\ENIG\Solder Mask\Tin-Plating
Base Material: CM-1 CM-3 FR-1 FR-4 AL-PCB
Brand Name: BLD
Model Number: single double multilayer pcb and AL pcb
Sensors PCB For Medical Instrument Manufacturer
BLD Electronic Co., Ltd.
China (Mainland) Trade Assurance
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63 Transactions(6 months)
420,000+
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98.8%
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Customized design Soft turnkey service PCB PCBA assembly for musical products/ guitar board/ instrument
US $0.1 / Piece
1 Piece (Min. Order)
Brand Name: OEM ODM
Base Material: FR-4
Surface Soft Finishing: HASL
Min. Line Width: 0.075mm/0.075mm(3mil/3mil)
Min. Line Spacing: 0.1mm4mil)
Copper Thickness: 1/2OZ 1OZ 2OZ 3OZ,0.25OZ~12OZ
Customized design turnkey service PCB PCBA assembly for musical products/ guitar board/ instrument 6 Photos
Shenzhen UC Industrial Limited
China (Mainland) Trade Assurance
Transaction Soft Level:
8 Transactions(6 months)
7,000+
Response Rate
65.6%
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MIDI Controller Soft Keyboard PCBA Manufacture for Electronic Musical Instrument Circuit Board Assembly
US $1-60 / Piece
1 Piece (Min. Order)
Min. Hole Size: 0.1mm(4mil)
Number of Layers: 12-Layer
Min. Line Width: 4mil
Place of Origin: Guangdong,China (Mainland)
Base Material: FR-4,teflon,aluminum base,copper base,steel base,high frequency
Board Thickness: 0.1 to 6.0mm(4 to 240mil)
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Shenzhen Kingsheng PCBA Tech. Co., Ltd.
China (Mainland)
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Quality fr4 multilayer pcb for medical instrument manufacturer
US $1-12 / Piece
1 Piece (Min. Order)
Min. Hole Size: 0.20mm
Copper Thickness: 0.3oz-3oz
Min. Line Width: 0.1mm(Flash Gold)/0.15mm(HASL)
Place of Origin: Guangdong,China (Mainland)
Brand Name: circuit pcb board
Model Number: circuit pcb board
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Shenzhen Ciree Technology Ltd.
China (Mainland) Trade Assurance
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Several modalities have been developed in order to reverse the dermal and epidermal signs of photo- and chronological aging. The main concept of most of these modalities is removing the epidermis and inducing a controlled form of skin wounding in order to promote collagen biosynthesis and dermal matrix remodeling. The most commonly used interventions as of today are retinoic acid (a vitamin A derivative), dermabrasion, chemical peels, and ablative laser resurfacing with carbon dioxide (CO2) or erbium: yttrium-aluminum-garnet (Er:YAG) lasers Soft or a combination of these wavelengths.25–27 However, these procedures require intensive post-treatment care, prolonged downtime and may lead to complications such as long-lasting erythema, pain, infection, bleedings, oozing, burns, hyper- or hypopigmentation and scarring.28,29 These limitations created a need for the development of alternative rejuvenation procedures that were safer, more effective, had fewer side effects and minimum postoperative care and downtime, which in turn led to the emergence of non-ablative rejuvenation technologies.30–32 Non-ablative skin rejuvenation aims to improve photoaged Soft and aging skin without destroying the epidermis.31,32 Irregular pigmentation and telangiectasia can be treated with intense pulsed light sources (IPL), 532 nm potassium-titanyl-phosphate lasers (KTP), and high-dose 585/595 nm pulsed dye lasers (PDL)33. Wrinkle reduction and skin tightening through thermal injury to the dermis (photothermolysis) can be achieved by other IPL sources (ie, low-dose 589/595 nm PDLs, 1064 & 1320 nm neodymium:yttrium-aluminum-garnet lasers, (Nd:YAG) 1450 nm diode lasers, and 1540 nm erbium fiber lasers).33
LED which is a novel light source for non-thermal, non-ablative skin rejuvenation has been shown to be effective for improving wrinkles and skin laxity (Figure 3).34–40 It is not a new phenomenon since the first reports of LLLT effects on increased collagen go back to 1987. Studies by Abergel et al. and Yu et al. reported an increase in production of pro-collagen, collagen, basic fibroblast growth factors (bFGF) and proliferation of fibroblasts after exposure to low-energy laser irradiation in vitro and in vivo animal models (Figure 4).41,42 Furthermore, LLLT was already known to increase microcirculation, vascular perfusion in the skin, alter platelet-derived growth factor (PDGF), Soft transforming growth factor (TGF-β1) and inhibit apoptosis (Figure 4).1,43,44 Lee et al. investigated the histologic and ultrastructural changes following a combination of 830 nm, 55 mW/cm2, 66 J/cm2 and 633 nm, 105 mW/cm2, 126 J/cm2 LED phototherapy and observed alteration in the status of MMPs and their tissue inhibitors (TIMPs).33 Furthermore, mRNA levels of IL-1β, TNF-α, ICAM-1, and connexin 43 (Cx43) were increased following LED phototherapy whereas IL-6 levels were decreased (Figure 4) 33. Finally, an increase in the amount of collagen was demonstrated in the post-treatment specimens 33. Pro-inflammatory cytokines IL-1β and TNF-α are thought to be recruited to heal the intentionally formed photothermally-mediated wounds associated with laser treatments, and this cascade of wound healing consequently contributes to new collagen synthesis.33 LED therapy may induce this wound healing process through non-thermal and atraumatic Soft induction of a subclinical ‘quasi-wound’, even without any actual thermal damage which could cause complications as in some other laser treatments.33 TIMPs inhibit MMP activities, so another possible mechanism for the increased collagen could be through the induction of TIMPs (Figure 4). When these observations are put together, it is possible that increased production of IL-1β and TNF-α might have induced MMPs in the early response to LED therapy. This may clear the photodamaged collagen fragments to enable biosynthesis of new collagen fibers. Later on, an increase in the amount of TIMPs might protect the newly synthesized collagen from proteolytic degradation by MMPs.33 Furthermore, increased expression of Cx43 may possibly enhance cell-to-cell communication between dermal components, especially the fibroblasts, and enhance the cellular responses to the photobiostimulation effects from LED treatment, in order to produce new collagen in a larger area which even includes the non-irradiated regions.33 In a clinical study performed by Weiss et al., 300 patients received LED therapy (590 nm, 0.10 J/cm2) alone, and 600 patients received LED therapy in combination with a thermal-based photorejuvenation procedure. Among patients who received LED photorejuvenation alone, 90% reported that they observed a softening of skin texture and a reduction in roughness and fine lines ranging from a significant reduction to sometimes subtle changes.36 Moreover, patients receiving a thermal photorejuvenation laser with or without additional LED photomodulation (n = 152) reported a prominent reduction in post-treatment erythema and an overall impression of increased efficacy Soft with the additional LED treatment.36,45 This reduction in post-treatment erythema could be attributed to anti-inflammatory effects of LLLT.40 Using different pulse sequence parameters, a multicenter clinical trial was conducted, with 90 patients receiving 8 LED treatments over 4 weeks.37,46–48 The outcome of this study showed very favorable results, with over 90% of patients improving by at least one Fitzpatrick photoaging category and 65% of patients demonstrating global improvement in facial texture, fine lines, background erythema, and pigmentation. The results peaked at 4 to 6 months following completion of 8 treatments. Markedly increased collagen in the papillary dermis and reduced MMP-1 were common findings. Barolet et al.’s study is also consistent with the previously mentioned studies. They used a 3-D model of tissue-engineered human reconstructed skin to investigate the potential of 660 nm, 50 mW/cm, 4 J/cm2 LED in modulating collagen and MMP-1 and results showed upregulation of collagen and down-regulation MMP-1 in vitro.40 A split-face, single-blinded clinical study was then carried out to assess the results of this light treatment on skin texture and appearance of individuals with aged/photoaged skin.40 Following 12 LED treatments, profilometry quantification demonstrated that while more than 90% of individuals had a reduction in rhytid depth and surface roughness, 87% of the individuals reported that they have experienced a reduction in the Fitzpatrick wrinkling severity score.40
Figure 3
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PCBA Manufacturer Automobile Electronic Instrument Pcb Assembly
US $0.46-7.4 / Piece
1 Piece (Min. Order)
Place of Soft Origin: Guangdong,China (Mainland)
Brand Name: fastpcba
Base Material: FR4,CEM,Tg-170,Aluminum based
Surface Finishing: Immersion Gold/Au, HASL, OSP, Immersion silver, etc.
Min. Hole Size: 0.2mm
Min. Line Width: 3mil
PCBA Manufacturer Automobile Electronic Instrument Pcb Assembly 6 Photos
Shenzhen Jingbang Technology Co., Ltd.
China (Mainland)
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OEM ODM 1.4t CEM1 ENIG musical instruments pcb board
US $1-10 / Piece
10 Pieces (Min. Order)
Place of Soft Origin: Liaoning,China (Mainland)
Model Number: ol-pcba-Home electronics
Base Material: 94V0
Min. Line Width: 0.1mm
Min. Line Spacing: 0.1mm
Copper Thickness: 0.035mm
OEM ODM 1.4t CEM1 ENIG musical instruments pcb board
O-Line Century Electronic Technology Co., Ltd. (Dalian)
China (Mainland) Trade Assurance
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29 Transactions(6 months)
10,000+
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70.6%
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CEM3 PCB For Soft Medical Instrument Manufacturer
US $0.3-5 / Piece
1 Piece (Min. Order)
Place of Origin: Guangdong,China (Mainland)
Brand Name: Jinghon
Base Material: FR-4
Min. Line Width: 0.1 0mm
Board Thickness: 1.6mm
Product name: LCD circuit board assembly
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Shenzhen Jinghon Electronics Limited
China (Mainland) Trade Assurance
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15 Transactions(6 months)
30,000+
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89.5%
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US $0.18-11.3 / Piece
10 Pieces (Min. Order)
Brand Name: Golden Weald
Model Number: odm pcb assembly servic
Base Material: FR4
Surface Finishing: OSP/HASL/Immersion Gold
Min. Hole Size: 0.2mm
Min. Line Spacing: 0.15mm
instrumentation pcb assemblies Electronics PCBA Manufacturer ,PCBA Assembly,pcb assembly manufacturer odm pcb assembly servic 6 Photos
Shenzhen Golden Weald Electronic Co., Limited
China (Mainland)
Transaction Level:
2 Transactions(6 months)
4,000+
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85.0%
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OEM PCBA Manufacture for Measuring Instruments Assemble with High Quality
US $0.2-8 / Piece
1 Piece (Min. Order)
Place of Origin: Guangdong,China (Mainland)
Model Number: Electronic PCB
Base Material: FR4
Min. Hole Size: 0.1mm
Copper Thickness: 0.5oz-6oz
Type: Electronic Board
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Shenzhen Noeya Technology Co., Ltd.
China (Mainland)
Transaction Level:
2 Transactions(6 months)
6,000+
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84.1%
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PCB Assembly Contract Manufacturing Service for Electronics Instrumentation and Medical Products
US $0.3-2 / Piece
1 Piece (Min. Order)
Place of Origin: Guangdong,China (Mainland)
Brand Name: RayMing
Model Number: PCB Assembly
Min. Line Width: 0.075mm=3mil
Copper Thickness: 1/2OZ 1OZ 2OZ 3OZ
Board Thickness: 0.2mm-4.5mm
PCB Assembly Contract Manufacturing Service for Electronics Instrumentation and Medical Products
Shenzhen Rayming Electronic Co., Ltd.
China (Mainland)
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54.2%
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Printed circuit board assembly service for test instrument pcb
US $76 / Square Meter
3 Square Meters (Min. Order)
Brand Name: XJY
Model Number: 156548
Base Material: FR4
Min. Hole Size: 0.3mm
Min. Line Width: 0.1mm
Min. Line Spacing: 0.1mm
Printed circuit board assembly service for test instrument pcb
Shenzhen Xinjiaye Electronics Technology Co., Ltd.
China (Mainland)
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Cheap cost medical industrial instrument printed circuit boards, pcb assembly electronic manufacturing service
US $1-100 / Piece
100 Pieces (Min. Order)
Brand Name: Leadsintec
Base Material: FR-4,CEM-3,FR-1,Taconic,Rogers, ALU, PL-Custom
Min. Hole Size: 1mm
Min. Line Width: 0.01mm
Min. Line Spacing: 0.01mm
Copper Thickness: 3oz
Cheap cost medical industrial instrument printed circuit boards, pcb assembly electronic manufacturing service 4 Photos
Shenzhen Leadsintec Co., Ltd.
China (Mainland)
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50.0%
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2015 Passive rohs shenzhen medical apparatus and instruments high quality pcb supports manufacturer pcb&pcba motherboard android
US $0.25 / Piece
1 Piece (Min. Order)
Place of Origin: Guangdong,China (Mainland)
Model Number: Pcba Assembly
Surface Finishing: HASL
Min. Hole Size: 0.20mm
Copper Thickness: 1oz
Product name: Pcb Assembly Made
2015 Passive rohs shenzhen medical apparatus and instruments high quality pcb supports manufacturer pcb&pcba motherboard android 6 Photos
Shenzhen Zealfull Technology Co., Ltd.
China (Mainland)
Response Rate
0.0%
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Coagulometer pcba manufacturer
US $0.1-20 / Piece
1 Piece (Min. Order)
Place of Origin: Guangdong,China (Mainland)
Brand Name: Xingda
Base Material: FR-4,FR2.Taconic,Rogers, CEM-1 CEM-3,ceramic,crockery,Metal,Carbon
Surface Finishing: Immersion Gold/Au,HASL,OSP,etc
Min. Line Width: 0.075mm(3mil)
Board Thickness: 0.2mm-6.00 mm(8mil-126mil)
Coagulometer pcba manufacturer
Shenzhen Xin Da Xing Electronic Tech Co., Ltd.
China (Mainland) Trade Assurance
Transaction Level:
3 Transactions(6 months)
100+
Response Rate
89.5%
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Digital Water Wave Circuit Board,Tide Level Meter Circuit Board Assembly & Copy manufacturer
US $10-60 / Unit
1 Unit (Min. Order)
Copper Thickness: 0.5oz-6oz
Surface Finishing: HASL,Leadfree HASL,Immersion gold/silver/Tin,OSP,ENIG
Place of Origin: Guangdong,China (Mainland)
Base Material: FR-4,teflon,aluminum base,copper base,steel base,high frequency
Brand Name: C-Alley
Board Thickness: 0.1 to 6.0mm(4 to 240mil)
Digital Water Wave Circuit Board,Tide Level Meter Circuit Board Assembly & Copy manufacturer
Shenzhen Kingsheng PCBA Tech. Co., Ltd.
China (Mainland)
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US $0.13-10.2 / Piece
10 Pieces (Min. Order)
Brand Name: Golden Weald
Model Number: pcb assemblies smd
Base Material: FR4
Min. Hole Size: 0.2mm
Min. Line Width: 0.15mm
Board Thickness: 1.0mm-1.6mm
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Shenzhen Golden Weald Electronic Co., Limited
China (Mainland)
Transaction Level:
2 Transactions(6 months)
4,000+
Response Rate
85.0%
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cooling instrument pcba board
US $0.1-20 / Piece
1 Piece (Min. Order)
Place of Origin: Guangdong,China (Mainland)
Base Material: FR-4,FR2.Taconic,Rogers, CEM-1 CEM-3,ceramic,crockery,Metal,Carbon
Surface Finishing: Immersion Gold/Au,HASL,OSP,etc
Min. Line Width: 0.075mm(3mil)
Min. Line Spacing: 0.1mm4mil)
Copper Thickness: 1/2 oz min;12 oz max
cooling instrument pcba board
Shenzhen Xin Da Xing Electronic Tech Co., Ltd.
China (Mainland) Trade Assurance
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100+
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89.5%
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Electronic Laser Instrument Circuit Board ,Electronic Laser Instrument PCB Assembly & Copy manufacturer
US $10-60 / Unit
1 Unit (Min. Order)
Min. Line Spacing: 4mil
Min. Hole Size: 0.1mm(4mil)
Copper Thickness: 0.5oz-6oz
Surface Finishing: HASL,Leadfree HASL,Immersion gold/silver/Tin,OSP,ENIG
Model Number: PCBA
Board Thickness: 0.1 to 6.0mm(4 to 240mil)
Electronic Laser Instrument Circuit Board ,Electronic Laser Instrument PCB Assembly & Copy manufacturer
Shenzhen Kingsheng PCBA Tech. Co., Ltd.
China (Mainland)
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Control Board for Access system low cost pcb assembly
US $0.9-74 / Piece
10 Pieces (Min. Order)
Brand Name: Golden Weald
Model Number: pcb assembly pcba manufacturer
Surface Finishing: OSP HASL Immersion Gold
Min. Hole Size: 0.2mm
Min. Line Spacing: 0.15mm
Copper Thickness: 35um
Control Board for Access system low cost pcb assembly 6 Photos
Shenzhen Golden Weald Electronic Co., Limited
China (Mainland)
Transaction Level:
2 Transactions(6 months)
4,000+
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85.0%
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Latest HOT SELLING custom made electronic PCB/FPC/FFC assembly circuit membrane switch buttons manufacturing and service
US $0.5-5 / Piece
200 Sets (Min. Order)
Model Number: H884 electronic circuit assembly
Application: Telecommunication Equipment,industrial equipment,medical instrument,home appliance etc.
Place of Origin: Zhejiang,China (Mainland)
Keypad Button Material: PC or PET
Brand Name: HOEE
electronic circuit assembly: PET or PC material
Latest HOT SELLING custom made electronic PCB/FPC/FFC assembly circuit membrane switch buttons manufacturing and service 4 Photos
Cixi Membrane Switch Factory
China (Mainland) Trade Assurance
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110,000+
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LED Aluminum PCB Circuit Board SMD DIP service and PCB breadboard
US $0.5-1 / Piece
1 Piece (Min. Order)
Copper Thickness: 1um-35um,0.5oz-5oz
Min. Line Spacing: 0.003"
Base Material: FR-4
Brand Name: OEM/ODM
Surface Finishing: HASL
Type: Electronic component PCB Assembly Manufacturer
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Shenzhen Aircloud Technology Limited
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Rigid-flex PCB Motor Vehicle Diagnostic Instrument PCB Fab Quick Turn Prototyping
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PCB Manufacturing Service with Turnkey Contract for Elect...
China PCB Manufacturing Service with Turnkey Contract for Electronic Product Control Unit
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Mini electronic PCB assembly with 0201 components
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Laser therapy equipment, electric therapy machine, laser ...
China Laser therapy equipment, electric therapy machine, laser pain relief instrument
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Hair Removal Instrument Home IPL Pulse Laser Hair Removal
China Hair Removal Instrument Home IPL Pulse Laser Hair Removal
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US$ 52 - 62 / Piece
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Diode Laser Therapy, Apparatus to Reduce Blood Viscosity,...
China Diode Laser Therapy, Apparatus to Reduce Blood Viscosity, Triglycerides and Cholesterol
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US$ 110 - 160 / Carton
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Multiple functional laser therapy device soft laser pain ...
China Multiple functional laser therapy device soft laser pain relief treatment
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Laser Pain Relief Therapy for Strong Analgesia Tissue Rep...
China Laser Pain Relief Therapy for Strong Analgesia Tissue Repair Immunoregulation
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Pain relief cold laser therapeutic instrument, 808nm diod...
China Pain relief cold laser therapeutic instrument, 808nm diode laser laser physical therapy equipment
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Cold laser therapy sports physical therapy instrument
China Cold laser therapy sports physical therapy instrument
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Laser physical therapy instrument
China Laser physical therapy instrument
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Low Level Medical Semiconductor Laser Treatment Equipment
China Low Level Medical Semiconductor Laser Treatment Equipment
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LLLT medical instruments, laser pain relief product
China LLLT medical instruments, laser pain relief product
It has recently been suggested that infrared (IR) exposure might have protective effects against UV-induced skin damage mainly by triggering protective/repair responses to UV irradiation. In the natural environment, visible and IR solar wavelengths predominate in the morning and UVB and UVA are maximal around noon which suggest that mammalians already possess a natural mechanism which, in reaction to morning IR radiation, prepares the skin for upcoming potentially damaging UV radiation at noon.61 However, opposing views also exist, such as Krutmann’s study demonstrating IR-induced disturbance of the electron flow of the mitochondrial electron transport chain which leads to inadequate energy production in dermal fibroblasts.62 Schroeder’s report is another example stating that IR alters the collagen equilibrium of the dermal extracellular matrix by leading to an increased expression of the collagen-degrading enzyme MMP-1, and by decreasing the de novo synthesis of the collagen itself.59 As previously mentioned, the same light source may have opposite effects on the same tissue depending on the parameters used and these conflicting views are probably due to the biphasic effects of light.18,19
Menezes et al. demonstrated that non-coherent near infrared radiation (NIR) (700–2,000 nm) generated a strong cellular defense against solar UV cytotoxicity in the absence of rising skin temperature and it was assumed to be a long-lasting (at least 24 hours) and cumulative phenomenon.63 Following this study, Frank et al. proposed that IR irradiation prepares cells to resist UVB-induced damage by affecting the mitochondrial apoptotic pathway.64 IR pre-irradiation of human fibroblasts was shown to inhibit UVB activation of caspase-9 and -3, partially release of cytochrome c and Smac/Diablo, decrease pro-apoptotic (ie, Bax) and increase anti-apoptotic proteins (ie, Bcl-2 or Bcl-xL).64 The results suggested that IR inhibited UVB-induced apoptosis by modulating the Bcl2/Bax balance, pointing to a role of p53, a sensor of gene integrity involved in cell apoptosis and repair mechanisms. In a further study, Frank et al. studied more specifically the role of the p53 cell signaling pathway in the prevention of UVB toxicity.64 The response to IR irradiation was shown to be p53 dependent which further suggests that IR irradiation prepares cells to resist and/or to repair further UVB-induced DNA damage. Finally, the IR induction of defense mechanisms was supported by Applegate et al. who reported that the protective protein, ferritin, normally involved in skin repair (scavenger of Fe2+ otherwise available for oxidative reactions) was induced by IR radiation.65
In an in vitro study, it was reported that an increase dermal fibroblast procollagen secretion reduces metalloproteinases (MMP) or collagenase production following non-thermal non-coherent deep red visible LED exposures (660 nm, sequential pulsing mode).40 These results correlated with significant clinical improvement of rhytids in vivo.40 In a subsequent in vivo pilot study, effect of this wavelength in 3 healthy subjects using a minimal erythemal dose (MED) method adapted from sunscreen SPF determination has been investigated.61 The results showed that LED therapy was effective, achieving a significant response in the reduction of the erythema induced by UVB.61 Following this pilot study a further investigation has been performed to find out in vivo aspects of this phenomenon. Effects of non-thermal, non-coherent 660 nm LED pulsed treatments in providing enhanced skin resistance prior to upcoming UV damage was investigated in a group of subjects with normal fair skin and patients presenting polymorphous light eruption (PLE). Results suggested that LED based therapy prior to UV exposure provided significant dose-related protection against UVB induced erythema. A significant reduction in UVB induced erythema reaction was observed in at least one occasion in 85% of subjects as well as in the patients suffering from PLE. Furthermore, a sun protection factor SPF-15-like effect and a reduction in post-inflammatory hyperpigmentation were observed. An in vitro study by Yu et al. revealed that HeNe laser irradiation stimulated an increase in nerve growth factor (NGF) release from cultured keratinocytes and its gene expression.66 NGF is a major paracrine maintenance factor for melanocyte survival in skin.67 It was shown that NGF can protect melanocytes from UV-induced apoptosis by upregulating BCL-2 levels in the cells.68 Therefore, an increase in NGF production induced by HeNe laser treatment may provide another explanation for the photoprotective effects of LLLT.
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Step 2: Low Level Light Therapy (LLLT)
The studio’s co-owner explained that the red light emitted from her machine travels 660 nanometers below the skin’s surface to wake up “sluggish” skin cells, firm up skin for visibly younger-looking skin. She placed a conductor on my back before the treatment to ground the energy. According to The American Association of Dermatology (AAD), red light (in the range of 600-950nm) therapy is currently being investigated for treatment of acne, rosacea, and wrinkles. The AAD states in a press release that “red light works theoretically by stimulating the skin’s energy making machine, known as the mitochondria. As such, stimulated mitochondria make older cells behave more like energetic youthful cells, which hold the key to red light’s anti-aging potential (AAD, 2011).” Notice how the AAD were careful in saying “theoretically,” which implies that there’s no hard supporting evidence to date.
THE TREATMENT
Crystal microdermabrasion = messy. Two days after my treatment, I was still finding crystal remnants in my ears—much like when you find sand in your ears after a day on the beach.
Prep gel = clogged up pores. The cold laser gel is made is made up of essential oils, which felt thick for on my acne-prone skin. I was hoping that she would wash off this gel when she finished the cold laser but instead she topped me off with something even more occlusive.
Sunscreen = greasy. Unlike higher-end places, this place seemed to carry only one skincare line: Consonant, an “all-natural” line that just sits on top of my skin like glue. By the time I got home (an hour later) my face felt so greasy that I immediately washed it.
Temporary results. So how did my face look after my “sluggish” cells were awoken? Exactly the same, with the exception of my makeup going on smoother the next day. I felt like the cold laser didn’t add any additional benefits that I would normally get from a microdermabrasion.
MY IN-DEPTH THOUGHTS…stay with me, you may learn something!
To the average consumer, this treatment can sound very high-tech but in my opinion, it is not. First of all, the science behind LLLT for skincare purposes is weak, with the exception of blue light therapy for treating acne: “Of all the uses of light therapy, treating active acne is supported by the most evidence in the medical literature (AAD, 2011).” There are no peer-reviewed studies performed on humans with the standard clinical before-and-after face comparisons that I can find on red lights. This concerns me because there are so many at-home red light devices and constant Groupon deals for cold laser anti-aging facials offered to the public. The very words “cold laser” seems to make people think that it can work as well as a true laser, which emits some heat.
One of the key lessons I’ve learned about lasers and light energy treatments is that heat is what creates meaningful change to the underlying skin below the epidermis, called the dermis layer. This is where collagen and elastin fibers, which give skin it’s firmness and elasticity, are located.
That’s why clinical lasers and light therapies treatments (e.g. IPL, Fraxel, and Thermage) heat up to about 40 degrees celsius. This high-level heat enables the energy to penetrate into the deep dermis and truly stimulate collagen production. More ablative lasers used to treat deep wrinkles and acne scars (e.g. CO2 lasers, Erbiums, and the ProFractional) actually removes a layer of skin and travels even deeper to the subcutaneous layer, doing more than stimulating collagen cells but also helps to remodel the buggers. This collagen remodelling translates to a noticeable improvement in deep wrinkles, scars, and textural irregularities after just one treatment. Optimal results are seen over a series of treatments, and there are clinical before-and-afters in dermatology journals to prove this effect.
Advantages
1. safe does, not to hurt the skin
2. specific light wave, pertinence
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Surface roughness:: Rz0.1
Eupoean hot sell polished sapphire high balls for Soft Laser Beauty Instruments
Chongqing CYS Machinery Co., Ltd.
China (Mainland)
Response Rate
50.0%
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Skin Rejuvenation and Wrinkles Remove Soft Laser Beauty Instrument
10 Sets (Min. Order)
Type: Skin Scrubber
Brand Name: HNC
Feature: Face Lift,Skin Rejuvenation,Pigment Removal, Acne Skin Rejuvenation, Wrinkle Remover
Model Number: LED-J
Wavelength: Red light 630nm;bule light 465nm
Highest density of central dlight spot: Red light and blue light are 40 10%
Skin Rejuvenation and Wrinkles Remove Soft Laser Beauty Instrument 6 Photos
Hubei YJT Technology Co., Ltd.
China (Mainland) Trade Assurance
Transaction Level:
9 Transactions(6 months)
2,000+
Response Rate
81.7%
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Notime Soft Laser Beauty Instrument
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Pain Laser Treatment, LLLT Cold Laser Medical Therapeutic...
China Pain Laser Treatment, LLLT Cold Laser Medical Therapeutic Machine
7
US$ 300 - 350 / Piece
1 Piece (Min. Order)
Freight Cost Available
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Professional Medical Device Laser Therapeutic Instrument ...
China Professional Medical Device Laser Therapeutic Instrument for Pain Relief
5
US$ 290 - 300 / Piece
20 Pieces (Min. Order)
Freight Cost Available
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LLLT therapeutic laser portable laser glucose monitor
If you are looking for best high quality CE certification and newest fashion laser beauty equipment from professional laser beauty equipment, laser rf beauty mahcine, laser beauty instrument, brightening skin color machine, pigmentation removal machine, laser multi-functional beauty machine,...
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Products Details
If you are looking for best high quality CE certification and newest fashion laser beauty equipment from professional laser beauty equipment, laser rf beauty mahcine, laser beauty instrument, brightening skin color machine, pigmentation removal machine, laser multi-functional beauty machine, biological micro current acupuncture point machine manufacturer and factory, please feel free to contact Menobeauty.
laser beauty equipment
AURORA
A.working principle
905 soft laser & tipolar RF & biological microcurrent combined
B.Applications
1.whitening skin,
2.improve skin dark fizzled & skin texture & face edema,
3.remove freckles & wrinkles&pouch& black rim of eye,
4.activate cells,promote blood circulation;
ApplicationA.Herpes (lip or fever blisters) / Inflammations of oral mucosa (mucous membranes of the mouth)Treatment: Hold the Softlaser approximately 1 cm from the affected area. Do not hold the unit directly against the skin.B.Inflammations of the...
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